CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.260 | 434 Repressor (Amino-terminal Domain) |
|
1.10.260.60 |
Domain Context
CATH Clusters
| Superfamily | 1.10.260.60 |
| Functional Family | Histone-lysine N-methyltransferase, H3 lysine-79 specific |
Enzyme Information
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8TEK3
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (2)
| P06897 |
H2A1_XENLA
Xenopus laevis
Histone H2A type 1
|
| J3QS39 |
J3QS39_HUMAN
Homo sapiens
Polyubiquitin-B
|
PDB Structure
| PDB | 6NOG |
| External Links | |
| Method | ELECTRON MICROSCOPY |
| Organism | |
| Primary Citation |
Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell
|
