CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.260 | 434 Repressor (Amino-terminal Domain) | |
1.10.260.60 |
Domain Context
CATH Clusters
Superfamily | 1.10.260.60 |
Functional Family | Histone-lysine N-methyltransferase, H3 lysine-79 specific |
Enzyme Information
2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8TEK3
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (2)
P62799 |
H4_XENLA
Xenopus laevis
Histone H4
|
J3QS39 |
J3QS39_HUMAN
Homo sapiens
Polyubiquitin-B
|
PDB Structure
PDB | 6NJ9 |
External Links | |
Method | ELECTRON MICROSCOPY |
Organism | |
Primary Citation |
Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell
|