CATH Domain 6mh6A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.200	Peptidase S8/S53 domain

Domain Context

CATH Clusters

Superfamily	Peptidase S8/S53 domain
Functional Family	Proteinase K

Enzyme Information

3.4.21.64

Peptidase K.

based on mapping to UniProt P06873

Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyzes peptide amides.

-!- From the mold Tritirachium album Limber. -!- Contains two disulfide bridges and one free Cys near the active site His. -!- Belongs to peptidase family S8. -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.

UniProtKB Entries (1)

P06873

PRTK_PARAQ

Parengyodontium album

Proteinase K

PDB Structure

PDB	6MH6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. Martin-Garcia, J.M., Zhu, L., Mendez, D., Lee, M.Y., Chun, E., Li, C., Hu, H., Subramanian, G., Kissick, D., Ogata, C., Henning, R., Ishchenko, A., Dobson, Z., Zhang, S., Weierstall, U., Spence, J.C.H., Fromme, P., Zatsepin, N.A., Fischetti, R.F., Cherezov, V., Liu, W. Iucrj