CATH Domain 6mavB01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.370	Tissue inhibitor of metalloproteinase-1. Chain B, domain 1
	3.90.370.10	Tissue inhibitor of metalloproteinase-1. Chain B, domain 1

Domain Context

CATH Clusters

Superfamily	Tissue inhibitor of metalloproteinase-1. Chain B, domain 1
Functional Family	Metalloproteinase inhibitor 3

Enzyme Information

UniProtKB Entries (1)

TIMP1_HUMAN

Homo sapiens

Metalloproteinase inhibitor 1

PDB Structure

PDB	6MAV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition. Raeeszadeh-Sarmazdeh, M., Greene, K.A., Sankaran, B., Downey, G.P., Radisky, D.C., Radisky, E.S. J.Biol.Chem.