CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.565 | Retinoid X Receptor | |
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
Superfamily | Retinoid X Receptor |
Functional Family | Nuclear orphan receptor ROR-beta |
Enzyme Information
UniProtKB Entries (1)
P51449 |
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma
|
PDB Structure
PDB | 6J1L |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem.
|