CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Carbonic anhydrase 2

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P00918
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00918
CAH2_HUMAN
Homo sapiens
Carbonic anhydrase 2

PDB Structure

PDB 6H6S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Non-crystallographic symmetry in proteins: Jahn-Teller-like and Butterfly-like effects?
Silva, J.M., Giuntini, S., Cerofolini, L., Geraldes, C.F.G.C., Macedo, A.L., Ravera, E., Fragai, M., Luchinat, C., Calderone, V.
J. Biol. Inorg. Chem.
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