CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Carboxylic ester hydrolase |
Enzyme Information
| 3.1.1.13 |
Sterol esterase.
based on mapping to UniProt P19835
A steryl ester + H(2)O = a sterol + a fatty acid.
-!- A group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. -!- Activated by bile salts.
|
| 3.1.1.3 |
Triacylglycerol lipase.
based on mapping to UniProt P19835
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
|
UniProtKB Entries (1)
| P19835 |
CEL_HUMAN
Homo sapiens
Bile salt-activated lipase
|
PDB Structure
| PDB | 6H18 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray structures of human bile-salt activated lipase conjugated to nerve agents surrogates.
Toxicology
|
