CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.3510 |
Domain Context
CATH Clusters
| Superfamily | 1.10.287.3510 |
| Functional Family | NADH-ubiquinone oxidoreductase chain 4L |
Enzyme Information
| 7.1.1.2 |
NADH:ubiquinone reductase (H(+)-translocating).
based on mapping to UniProt P03903
NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
-!- The complex is present in mitochondria and aerobic bacteria. -!- Breakdown of the complex can release EC 1.6.99.3. -!- In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH. -!- Formerly EC 1.6.5.3.
|
UniProtKB Entries (1)
| Q91YT0 |
NDUV1_MOUSE
Mus musculus
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
|
PDB Structure
| PDB | 6G2J |
| External Links | |
| Method | ELECTRON MICROSCOPY |
| Organism | |
| Primary Citation |
Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states.
Nat. Struct. Mol. Biol.
|
