CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear orphan receptor ROR-beta

Enzyme Information

UniProtKB Entries (1)

P51449
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma

PDB Structure

PDB 6FZU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Optimizing a Weakly Binding Fragment into a Potent ROR gamma t Inverse Agonist with Efficacy in an in Vivo Inflammation Model.
Carcache, D.A., Vulpetti, A., Kallen, J., Mattes, H., Orain, D., Stringer, R., Vangrevelinghe, E., Wolf, R.M., Kaupmann, K., Ottl, J., Dawson, J., Cooke, N.G., Hoegenauer, K., Billich, A., Wagner, J., Guntermann, C., Hintermann, S.
J. Med. Chem.