CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.90 | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| Functional Family | ISG15 ubiquitin-like modifier |
Enzyme Information
UniProtKB Entries (2)
| P05161 |
ISG15_HUMAN
Homo sapiens
Ubiquitin-like protein ISG15
|
| P03305 |
POLG_FMDVO
Foot-and-mouth disease virus (strain O1)
Genome polyprotein
|
PDB Structure
| PDB | 6FFA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies.
Proc. Natl. Acad. Sci. U.S.A.
|
