CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.100 | Insulin-like, subunit E |
|
1.10.100.10 | Insulin-like |
Domain Context
CATH Clusters
| Superfamily | Insulin-like |
| Functional Family | insulin-like growth factor I isoform X1 |
Enzyme Information
UniProtKB Entries (2)
| Q09024 |
IMPL2_DROME
Drosophila melanogaster
Neural/ectodermal development factor IMP-L2
|
| P05019 |
IGF1_HUMAN
Homo sapiens
Insulin-like growth factor I
|
PDB Structure
| PDB | 6FF3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun
|
