CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.8
Cholinesterase.
based on mapping to UniProt P06276
An acylcholine + H(2)O = choline + a carboxylate.
-!- Acts on a variety of choline esters and a few other compounds.

UniProtKB Entries (1)

P06276
CHLE_HUMAN
Homo sapiens
Cholinesterase

PDB Structure

PDB 6EP4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.
Rosenberry, T.L., Brazzolotto, X., Macdonald, I.R., Wandhammer, M., Trovaslet-Leroy, M., Darvesh, S., Nachon, F.
Molecules