CATH Domain 6dqaA00

Superfamily	Cupin
Functional Family	Putative lysine-specific demethylase 5b

1.14.11.-

With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.

based on mapping to UniProt P29375

KDM5A_HUMAN

Homo sapiens

Lysine-specific demethylase 5A

PDB	6DQA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. Horton, J.R., Woodcock, C.B., Chen, Q., Liu, X., Zhang, X., Shanks, J., Rai, G., Mott, B.T., Jansen, D.J., Kales, S.C., Henderson, M.J., Cyr, M., Pohida, K., Hu, X., Shah, P., Xu, X., Jadhav, A., Maloney, D.J., Hall, M.D., Simeonov, A., Fu, H., Vertino, P.M., Cheng, X. J. Med. Chem.