CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Carbonic anhydrase 2

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P00918
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00918
CAH2_HUMAN
Homo sapiens
Carbonic anhydrase 2

PDB Structure

PDB 6CEH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology.
Angeli, A., di Cesare Mannelli, L., Trallori, E., Peat, T.S., Ghelardini, C., Carta, F., Supuran, C.T.
ACS Med Chem Lett
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