CATH Domain 6c67B00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Domain Context

CATH Clusters

Superfamily	3.40.1190.20
Functional Family	Adenosine kinase

Enzyme Information

2.7.1.20

Adenosine kinase.

based on mapping to UniProt P9WID5

ATP + adenosine = ADP + AMP.

-!- 2-aminoadenosine can also act as acceptor.

UniProtKB Entries (1)

ADOK_MYCTU

Mycobacterium tuberculosis H37Rv

Adenosine kinase

PDB Structure

PDB	6C67
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. Crespo, R.A., Dang, Q., Zhou, N.E., Guthrie, L.M., Snavely, T.C., Dong, W., Loesch, K.A., Suzuki, T., You, L., Wang, W., O'Malley, T., Parish, T., Olsen, D.B., Sacchettini, J.C. J.Med.Chem.