CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.260 | G Protein Gi Gamma 2 |
|
4.10.260.10 | Transducin (heterotrimeric G protein), gamma chain |
Domain Context
CATH Clusters
| Superfamily | Transducin (heterotrimeric G protein), gamma chain |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| P63212 |
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
|
| P25098 |
ARBK1_HUMAN
Homo sapiens
Beta-adrenergic receptor kinase 1
|
PDB Structure
| PDB | 6C2Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.
Bioorg. Med. Chem. Lett.
|
