CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.130 | 7 Propeller |
|
2.130.10 | Methylamine Dehydrogenase; Chain H |
|
2.130.10.10 | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | YVTN repeat-like/Quinoprotein amine dehydrogenase |
| Functional Family | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
Enzyme Information
UniProtKB Entries (2)
| P62871 |
GBB1_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
|
| P25098 |
ARBK1_HUMAN
Homo sapiens
Beta-adrenergic receptor kinase 1
|
PDB Structure
| PDB | 6C2Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.
Bioorg. Med. Chem. Lett.
|
