CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1330 | 60s Ribosomal Protein L30; Chain: A; | |
3.30.1330.20 | Tubulin/FtsZ, C-terminal domain |
Domain Context
CATH Clusters
Superfamily | Tubulin/FtsZ, C-terminal domain |
Functional Family | Tubulin beta chain |
Enzyme Information
UniProtKB Entries (3)
E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
P02554 |
TBB_PIG
Sus scrofa
Tubulin beta chain
|
Q9H169 |
STMN4_HUMAN
Homo sapiens
Stathmin-4
|
PDB Structure
PDB | 6BRF |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
J. Med. Chem.
|