CATH Classification

Domain Context

CATH Clusters

Superfamily Tubulin/FtsZ, GTPase domain
Functional Family Tubulin alpha chain

Enzyme Information

UniProtKB Entries (3)

E1BQ43
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
P02554
TBB_PIG
Sus scrofa
Tubulin beta chain
Q9H169
STMN4_HUMAN
Homo sapiens
Stathmin-4

PDB Structure

PDB 6BRF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
Banerjee, S., Arnst, K.E., Wang, Y., Kumar, G., Deng, S., Yang, L., Li, G.B., Yang, J., White, S.W., Li, W., Miller, D.D.
J. Med. Chem.
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