CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1440 | Tubulin/FtsZ, GTPase domain |
Domain Context
CATH Clusters
Superfamily | Tubulin/FtsZ, GTPase domain |
Functional Family | Tubulin beta chain |
Enzyme Information
UniProtKB Entries (3)
E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
Q2XVP4 |
TBA1B_PIG
Sus scrofa
Tubulin alpha-1B chain
|
Q9H169 |
STMN4_HUMAN
Homo sapiens
Stathmin-4
|
PDB Structure
PDB | 6BR1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
J. Med. Chem.
|