CATH Domain 6bozB00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.270	Beta-clip-like
	2.170.270.10	SET domain

Domain Context

CATH Clusters

Superfamily	SET domain
Functional Family	Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43	Histone-lysine N-methyltransferase. based on mapping to UniProt Q9NQR1 S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
2.1.1.-	Methyltransferases. based on mapping to UniProt Q9NQR1

UniProtKB Entries (1)

KMT5A_HUMAN

Homo sapiens

N-lysine methyltransferase KMT5A

PDB Structure

PDB	6BOZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The dynamic conformational landscape of the protein methyltransferase SETD8. Chen, S., Wiewiora, R.P., Meng, F., Babault, N., Ma, A., Yu, W., Qian, K., Hu, H., Zou, H., Wang, J., Fan, S., Blum, G., Pittella-Silva, F., Beauchamp, K.A., Tempel, W., Jiang, H., Chen, K., Skene, R.J., Zheng, Y.G., Brown, P.J., Jin, J., Luo, C., Chodera, J.D., Luo, M. Elife