CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.565 | Retinoid X Receptor | |
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
Superfamily | Retinoid X Receptor |
Functional Family | Nuclear orphan receptor ROR-beta |
Enzyme Information
UniProtKB Entries (1)
P51449 |
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma
|
PDB Structure
PDB | 6BN6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (ROR gamma /RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.
Bioorg. Med. Chem. Lett.
|