1 keywords

CATH Domain 6binA02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family HLA class II histocompatibility antigen, DR alpha chain

Enzyme Information

UniProtKB Entries (1)

P13760
2B14_HUMAN
Homo sapiens
HLA class II histocompatibility antigen, DRB1-4 beta chain

PDB Structure

PDB 6BIN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.
Ting, Y.T., Petersen, J., Ramarathinam, S.H., Scally, S.W., Loh, K.L., Thomas, R., Suri, A., Baker, D.G., Purcell, A.W., Reid, H.H., Rossjohn, J.
J. Biol. Chem.