CATH Domain 5zhlA02

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1270	Trp Operon Repressor; Chain A
	1.10.1270.20	tRNA(m1g37)methyltransferase, domain 2

Superfamily	tRNA(m1g37)methyltransferase, domain 2
Functional Family	tRNA (guanine-N(1)-)-methyltransferase

PDB	5ZHL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. Zhong, W., Pasunooti, K.K., Balamkundu, S., Wong, Y.H., Nah, Q., Gadi, V., Gnanakalai, S., Chionh, Y.H., McBee, M.E., Gopal, P., Lim, S.H., Olivier, N., Buurman, E.T., Dick, T., Liu, C.F., Lescar, J., Dedon, P.C. J.Med.Chem.