CATH Domain 5zg1A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.190	D-Maltodextrin-Binding Protein; domain 2
	3.40.190.10	Periplasmic binding protein-like II

Domain Context

CATH Clusters

Superfamily	Periplasmic binding protein-like II
Functional Family	Glutamate receptor ionotropic, kainate 2

Enzyme Information

UniProtKB Entries (1)

GRIA2_HUMAN

Homo sapiens

Glutamate receptor 2

PDB Structure

PDB	5ZG1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	TAK-137, an AMPA-R potentiator with little agonistic effect, has a wide therapeutic window. Kunugi, A., Tanaka, M., Suzuki, A., Tajima, Y., Suzuki, N., Suzuki, M., Nakamura, S., Kuno, H., Yokota, A., Sogabe, S., Kosugi, Y., Awasaki, Y., Kaku, T., Kimura, H. Neuropsychopharmacology