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1 keywords

CATH Domain 5y8mA02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.1040 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Homologous Superfamily 1.10.1040.10 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

Domain Context

CATH Clusters

Superfamily N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family 3-hydroxyisobutyrate dehydrogenase

Enzyme Information

1.1.1.31
3-hydroxyisobutyrate dehydrogenase.
based on mapping to UniProt P9WNY5
3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.

UniProtKB Entries (1)

P9WNY5
MMSB_MYCTU
Mycobacterium tuberculosis H37Rv
Probable 3-hydroxyisobutyrate dehydrogenase

PDB Structure

PDB 5Y8M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure, interactions and action ofMycobacterium tuberculosis3-hydroxyisobutyric acid dehydrogenase.
Srikalaivani, R., Singh, A., Vijayan, M., Surolia, A.
Biochem. J.
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