CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.28.200
Functional Family NAD-dependent protein deacetylase sirtuin-6

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q8N6T7

UniProtKB Entries (1)

Q8N6T7
SIR6_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-6

PDB Structure

PDB 5Y2F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of a cellularly active SIRT6 allosteric activator.
Huang, Z., Zhao, J., Deng, W., Chen, Y., Shang, J., Song, K., Zhang, L., Wang, C., Lu, S., Yang, X., He, B., Min, J., Hu, H., Tan, M., Xu, J., Zhang, Q., Zhong, J., Sun, X., Mao, Z., Lin, H., Xiao, M., Chin, Y.E., Jiang, H., Xu, Y., Chen, G., Zhang, J.
Nat. Chem. Biol.
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