CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.472 | Cyclin A; domain 1 |
|
1.10.472.10 | Cyclin-like |
Domain Context
CATH Clusters
| Superfamily | Cyclin-like |
| Functional Family | Putative cyclin-c |
Enzyme Information
UniProtKB Entries (1)
| P49336 |
CDK8_HUMAN
Homo sapiens
Cyclin-dependent kinase 8
|
PDB Structure
| PDB | 5XS2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of potent and selective CDK8 inhibitors through FBDD approach
Bioorg. Med. Chem. Lett.
|
