CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.460 | Beta Polymerase; domain 2 |
|
3.30.460.10 | Beta Polymerase, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Beta Polymerase, domain 2 |
| Functional Family | GTP pyrophosphokinase RelA |
Enzyme Information
| 2.7.6.5 |
GTP diphosphokinase.
based on mapping to UniProt P9WHG9
ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
-!- GDP can also act as acceptor.
|
| 3.1.7.2 |
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase.
based on mapping to UniProt P9WHG9
Guanosine 3',5'-bis(diphosphate) + H(2)O = guanosine 5'-diphosphate + diphosphate.
|
UniProtKB Entries (1)
| P9WHG9 |
RELA_MYCTU
Mycobacterium tuberculosis H37Rv
Bifunctional (p)ppGpp synthase/hydrolase RelA
|
PDB Structure
| PDB | 5XNX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystallographic and solution structure of the N-terminal domain of the Rel protein from Mycobacterium tuberculosis
FEBS Lett.
|