CATH Domain 5xlvA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Pantothenate kinase

Enzyme Information

2.7.1.33

Pantothenate kinase.

based on mapping to UniProt P9WPA7

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.

UniProtKB Entries (1)

COAA_MYCTU

Mycobacterium tuberculosis H37Rv

Pantothenate kinase

PDB Structure

PDB	5XLV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase Paul, A., Kumar, P., Surolia, A., Vijayan, M. Acta Crystallogr F Struct Biol Commun