CATH Domain 5x74A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.50	Coagulation Factor XIII; Chain A, domain 1
	2.70.50.40	GMP phosphodiesterase, delta subunit

Domain Context

CATH Clusters

Superfamily	GMP phosphodiesterase, delta subunit
Functional Family	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

Enzyme Information

UniProtKB Entries (1)

PDE6D_HUMAN

Homo sapiens

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

PDB Structure

PDB	5X74
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors Jiang, Y., Zhuang, C., Chen, L., Lu, J., Dong, G., Miao, Z., Zhang, W., Li, J., Sheng, C. J. Med. Chem.