CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.50 | FAD/NAD(P)-binding domain |
|
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
| Superfamily | FAD/NAD(P)-binding domain |
| Functional Family | Kynurenine 3-monooxygenase |
Enzyme Information
| 1.14.13.9 |
Kynurenine 3-monooxygenase.
based on mapping to UniProt O15229
L-kynurenine + NADPH + O(2) = 3-hydroxy-L-kynurenine + NADP(+) + H(2)O.
-!- Formerly EC 1.14.1.2 and EC 1.99.1.5.
|
UniProtKB Entries (1)
| O15229 |
KMO_HUMAN
Homo sapiens
Kynurenine 3-monooxygenase
|
PDB Structure
| PDB | 5X68 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol
|
