1 keywords

CATH Domain 5x0iC01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.1380 Pyruvate Kinase; Chain: A, domain 1
Homologous Superfamily 3.40.1380.20 Pyruvate kinase, C-terminal domain

Domain Context

CATH Clusters

Superfamily Pyruvate kinase, C-terminal domain
Functional Family Pyruvate kinase

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 5X0I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Chen, T.J., Wang, H.J., Liu, J.S., Cheng, H.H., Hsu, S.C., Wu, M.C., Lu, C.H., Wu, Y.F., Wu, J.W., Liu, Y.Y., Kung, H.J., Wang, W.C.
Commun Biol