1 keywords

CATH Domain 5x0iA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.60 Phosphoenolpyruvate-binding domains

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate-binding domains
Functional Family Pyruvate kinase

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 5X0I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Chen, T.J., Wang, H.J., Liu, J.S., Cheng, H.H., Hsu, S.C., Wu, M.C., Lu, C.H., Wu, Y.F., Wu, J.W., Liu, Y.Y., Kung, H.J., Wang, W.C.
Commun Biol