CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.630 | Cytochrome p450 |
|
1.10.630.10 | Cytochrome P450 |
Domain Context
CATH Clusters
| Superfamily | Cytochrome P450 |
| Functional Family | Mycocyclosin synthase |
Enzyme Information
| 1.14.19.70 |
Mycocyclosin synthase.
based on mapping to UniProt A0A0T9WNE5
Cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+) + O(2) = mycocyclosin + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H(2)O.
-!- A cytochrome P450 (heme-thiolate) protein from the bacterium Mycobacterium tuberculosis catalyzing an oxidative reaction that does not incorporate oxygen into the product. -!- Formerly EC 1.14.21.9.
|
| 1.14.-.- |
Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2).
based on mapping to UniProt A0A0T9WNE5
|
UniProtKB Entries (1)
| A0A0T9WNE5 |
A0A0T9WNE5_MYCTX
Mycobacterium tuberculosis
Cytochrome P450
|
PDB Structure
| PDB | 5WP2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Probing Ligand Exchange in the P450 Enzyme CYP121 from Mycobacterium tuberculosis: Dynamic Equilibrium of the Distal Heme Ligand as a Function of pH and Temperature.
J. Am. Chem. Soc.
|
