CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.150 | DNA polymerase; domain 1 | |
1.10.150.20 | 5' to 3' exonuclease, C-terminal subdomain |
Domain Context
CATH Clusters
Superfamily | 5' to 3' exonuclease, C-terminal subdomain |
Functional Family | DNA polymerase beta |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P06746
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
4.2.99.- |
Other carbon-oxygen lyases.
based on mapping to UniProt P06746
|
UniProtKB Entries (1)
P06746 |
DPOLB_HUMAN
Homo sapiens
DNA polymerase beta
|
PDB Structure
PDB | 5WNZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues.
Chem. Res. Toxicol.
|