CATH Domain 5wa1A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.280	alix/aip1 like domains

Domain Context

CATH Clusters

Superfamily	alix/aip1 like domains
Functional Family	programmed cell death 6-interacting protein-like isoform X1

Enzyme Information

UniProtKB Entries (1)

PDC6I_HUMAN

Homo sapiens

Programmed cell death 6-interacting protein

PDB Structure

PDB	5WA1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. Sadler, J.B.A., Wenzel, D.M., Williams, L.K., Guindo-Martinez, M., Alam, S.L., Mercader, J.M., Torrents, D., Ullman, K.S., Sundquist, W.I., Martin-Serrano, J. Proc. Natl. Acad. Sci. U.S.A.