CATH Domain 5vidD01

Superfamily	2.60.120.200
Functional Family	Botulinum neurotoxin type A

3.4.24.69

Bontoxilysin.

based on mapping to UniProt P10844

Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.

-!- Belongs to peptidase family M27.

BXB_CLOBO

Clostridium botulinum

Botulinum neurotoxin type B

PDB	5VID
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Massively parallel de novo protein design for targeted therapeutics. Chevalier, A., Silva, D.A., Rocklin, G.J., Hicks, D.R., Vergara, R., Murapa, P., Bernard, S.M., Zhang, L., Lam, K.H., Yao, G., Bahl, C.D., Miyashita, S.I., Goreshnik, I., Fuller, J.T., Koday, M.T., Jenkins, C.M., Colvin, T., Carter, L., Bohn, A., Bryan, C.M., Fernandez-Velasco, D.A., Stewart, L., Dong, M., Huang, X., Jin, R., Wilson, I.A., Fuller, D.H., Baker, D. Nature