CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.330.70
Functional Family Putative lysine-specific demethylase 4a

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O75164

UniProtKB Entries (1)

O75164
KDM4A_HUMAN
Homo sapiens
Lysine-specific demethylase 4A

PDB Structure

PDB 5VAR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach.
Upadhyay, A.K., Judge, R.A., Li, L., Pithawalla, R., Simanis, J., Bodelle, P.M., Marin, V.L., Henry, R.F., Petros, A.M., Sun, C.
Bioorg. Med. Chem. Lett.
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