CATH Domain 5v3oA03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.10	YVTN repeat-like/Quinoprotein amine dehydrogenase

Domain Context

CATH Clusters

Superfamily	YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family	DNA damage-binding protein 1

Enzyme Information

UniProtKB Entries (1)

CRBN_HUMAN

Homo sapiens

Protein cereblon

PDB Structure

PDB	5V3O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. Matyskiela, M.E., Zhang, W., Man, H.W., Muller, G., Khambatta, G., Baculi, F., Hickman, M., LeBrun, L., Pagarigan, B., Carmel, G., Lu, C.C., Lu, G., Riley, M., Satoh, Y., Schafer, P., Daniel, T.O., Carmichael, J., Cathers, B.E., Chamberlain, P.P. J. Med. Chem.