CATH Domain 5uvlA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.200	Peptidase S8/S53 domain

Domain Context

CATH Clusters

Superfamily	Peptidase S8/S53 domain
Functional Family	Proteinase K

Enzyme Information

3.4.21.64

Peptidase K.

based on mapping to UniProt P06873

Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyzes peptide amides.

-!- From the mold Tritirachium album Limber. -!- Contains two disulfide bridges and one free Cys near the active site His. -!- Belongs to peptidase family S8. -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.

UniProtKB Entries (1)

P06873

PRTK_PARAQ

Parengyodontium album

Proteinase K

PDB Structure

PDB	5UVL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. Martin-Garcia, J.M., Conrad, C.E., Nelson, G., Stander, N., Zatsepin, N.A., Zook, J., Zhu, L., Geiger, J., Chun, E., Kissick, D., Hilgart, M.C., Ogata, C., Ishchenko, A., Nagaratnam, N., Roy-Chowdhury, S., Coe, J., Subramanian, G., Schaffer, A., James, D., Ketwala, G., Venugopalan, N., Xu, S., Corcoran, S., Ferguson, D., Weierstall, U., Spence, J.C.H., Cherezov, V., Fromme, P., Fischetti, R.F., Liu, W. IUCrJ