CATH Classification
Domain Context
CATH Clusters
Superfamily | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
Functional Family |
Enzyme Information
3.1.4.17 |
3',5'-cyclic-nucleotide phosphodiesterase.
based on mapping to UniProt Q01064
Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.
-!- Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP.
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UniProtKB Entries (1)
Q01064 |
PDE1B_HUMAN
Homo sapiens
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
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PDB Structure
PDB | 5UP0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J. Med. Chem.
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