CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.360 | Dihydrodipicolinate Reductase; domain 2 |
|
3.30.360.10 | Dihydrodipicolinate Reductase; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Dihydrodipicolinate Reductase; domain 2 |
| Functional Family | Glucose-6-phosphate 1-dehydrogenase |
Enzyme Information
| 1.1.1.49 |
Glucose-6-phosphate dehydrogenase (NADP(+)).
based on mapping to UniProt P11413
D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH.
-!- The enzyme catalyzes a step of the pentose phosphate pathway. -!- The enzyme is specific for NADP(+), cf. EC 1.1.1.363 and EC 1.1.1.388.
|
UniProtKB Entries (1)
| P11413 |
G6PD_HUMAN
Homo sapiens
Glucose-6-phosphate 1-dehydrogenase
|
PDB Structure
| PDB | 5UKW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mutations in the tetramer interface of human glucose-6-phosphate dehydrogenase reveals kinetic differences between oligomeric states.
FEBS Lett.
|
