CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Oxysterol-binding protein

Enzyme Information

UniProtKB Entries (1)

Q9BZF1
OSBL8_HUMAN
Homo sapiens
Oxysterol-binding protein-related protein 8

PDB Structure

PDB 5U77
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Ghai, R., Du, X., Wang, H., Dong, J., Ferguson, C., Brown, A.J., Parton, R.G., Wu, J.W., Yang, H.
Nat Commun