CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family Putative glutamate receptor ionotropic NMDA 2B

Enzyme Information

UniProtKB Entries (1)

Q12879
NMDE1_HUMAN
Homo sapiens
Glutamate receptor ionotropic, NMDA 2A

PDB Structure

PDB 5TPA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile.
Villemure, E., Volgraf, M., Jiang, Y., Wu, G., Ly, C.Q., Yuen, P.W., Lu, A., Luo, X., Liu, M., Zhang, S., Lupardus, P.J., Wallweber, H.J., Liederer, B.M., Deshmukh, G., Plise, E., Tay, S., Wang, T.M., Hanson, J.E., Hackos, D.H., Scearce-Levie, K., Schwarz, J.B., Sellers, B.D.
ACS Med Chem Lett