CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.25 | Laminin |
|
2.10.25.10 | Laminin |
Domain Context
CATH Clusters
| Superfamily | Laminin |
| Functional Family | Coagulation factor VII |
Enzyme Information
| 3.4.21.22 |
Coagulation factor IXa.
based on mapping to UniProt P00740
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P00740 |
FA9_HUMAN
Homo sapiens
Coagulation factor IX
|
PDB Structure
| PDB | 5TNO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors.
Bioorg. Med. Chem. Lett.
|
