CATH Domain 5tioC01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.170	Acetylcholine Binding Protein; Chain: A,
	2.70.170.10	Neurotransmitter-gated ion-channel ligand-binding domain

Domain Context

CATH Clusters

Superfamily	Neurotransmitter-gated ion-channel ligand-binding domain
Functional Family	Glycine receptor alpha 1 subunit

Enzyme Information

UniProtKB Entries (1)

GLRA3_HUMAN

Homo sapiens

Glycine receptor subunit alpha-3

PDB Structure

PDB	5TIO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structures of Human GlyRa3 Bound to a Novel Class of Potentiators with Efficacy in a Mouse Model of Neuropathic Pain Huang, X., Shaffer, P.L., Ayube, S., Bregman, H., Chen, H., Lehto, S.G., Luther, J.A., Matson, D.J., McDonough, S.I., Michelsen, K., Plant, M.M., Schneider, S., Simard, J.R., Teffera, Y., Yi, S., Zhang, M., DiMauro, E.F., Gingras, J. To Be Published