CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.240 | Tyrosyl-Transfer RNA Synthetase |
|
1.10.240.10 | Tyrosyl-Transfer RNA Synthetase |
Domain Context
CATH Clusters
| Superfamily | Tyrosyl-Transfer RNA Synthetase |
| Functional Family | Tyrosine--tRNA ligase |
Enzyme Information
| 6.1.1.1 |
Tyrosine--tRNA ligase.
based on mapping to UniProt P54577
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).
|
UniProtKB Entries (1)
| P54577 |
SYYC_HUMAN
Homo sapiens
Tyrosine--tRNA ligase, cytoplasmic
|
PDB Structure
| PDB | 5THH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.
Nucleic Acids Res.
|