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CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family AP2 associated kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q2M2I8
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q2M2I8
AAK1_HUMAN
Homo sapiens
AP2-associated protein kinase 1

PDB Structure

PDB 5TE0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Adaptor Protein 2 Associated Kinase (AAK1) in complex with BIBF 1120
Counago, R.M., Elkins, J.M., Arrowsmith, C.H., Bountra, C., Arruda, P., Edwards, A.M., Gileadi, O.
To Be Published
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