1 keywords

CATH Domain 5tdhA02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.400 GI Alpha 1, domain 2-like
Homologous Superfamily 1.10.400.10 GI Alpha 1, domain 2-like

Domain Context

CATH Clusters

Superfamily GI Alpha 1, domain 2-like
Functional Family Guanine nucleotide-binding protein G(I) subunit alpha

Enzyme Information

UniProtKB Entries (3)

P54311
GBB1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
P63212
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P63096
GNAI1_HUMAN
Homo sapiens
Guanine nucleotide-binding protein G(i) subunit alpha-1

PDB Structure

PDB 5TDH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
Liu, P., Jia, M.-Z., Zhou, X.E., De Waal, P.W., Dickson, B.M., Liu, B., Hou, L., Yin, Y.-T., Kang, Y.-Y., Shi, Y., Melcher, K., Xu, H.E., Jiang, Y.
Acta Pharmacol.Sin.